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Understanding drug addiction
Drug addiction, also known as substance use disorder (SUD), is a chronic medical condition characterized by the compulsive use of one or more substances despite harmful consequences. Addiction is not simply a matter of willpower—it is a complex brain disease that affects judgment, behavior, and motivation. Over time, drug use alters neural pathways involved in reward, stress, and self-control, making it increasingly difficult to stop even when the person wants to.
Drugs can change how the brain communicates by disrupting normal chemical signaling and reinforcing the desire to keep using. The result is a cycle of craving and consumption that can lead to serious physical, emotional, and social harm. Without professional treatment, addiction can progress and cause long-term damage to the body and mind, but with evidence-based care, recovery is possible.
What causes drug addiction?
Drug addiction develops through an interplay of genetic, psychological, and environmental factors.
- Genetic predisposition. Studies estimate that genetic factors account for 40–60% of a person’s risk of developing a substance use disorder. A family history of addiction can increase vulnerability.
- Environmental influences. Exposure to drug use at home, peer pressure, community availability, and stressful living conditions can all contribute to early experimentation and continued use.
- Mental health conditions. Depression, anxiety, post-traumatic stress disorder (PTSD), and other psychiatric disorders are strongly linked to substance misuse, as individuals may turn to drugs for temporary relief.
- Developmental factors. Adolescents and young adults are especially susceptible because their brains are still developing, particularly in areas controlling impulse and decision-making.
- Stress and trauma. Chronic stress, neglect, or trauma—especially in childhood—can increase the likelihood of self-medicating through drugs or alcohol.
While any single factor may not directly cause addiction, the interaction between these influences can significantly raise the risk of developing a substance use disorder.
How drugs affect the brain
Drugs alter the brain’s communication system by mimicking or interfering with neurotransmitters—the chemical messengers that transmit signals between neurons. Many substances overstimulate the brain’s reward system, flooding it with dopamine, which produces intense feelings of pleasure and reinforces the desire to repeat the behavior.
Over time, the brain adapts to this artificial stimulation by producing less dopamine or reducing receptor sensitivity. This results in diminished pleasure from everyday activities and an increased need for the drug to feel normal—a process known as tolerance.
Prolonged drug use can impair areas of the brain responsible for learning, memory, and decision-making. The individual may experience problems with attention, motivation, and impulse control long after stopping drug use. While some changes can improve with sustained abstinence and healthy habits, recovery of normal brain function takes time and structured care.
Our track record of success
We are here to help individuals and families overcome drug addiction
Success stories
“Red Ribbon Recovery Indiana gave me more than sobriety, it gave me a new perspective on life. The team helped me confront the trauma that fueled my drug addiction and rebuild trust with my family.”
Daniel R.
Completed outpatient program, 2025
“After years of battling opioid addiction, I finally found a place that understood both my physical and emotional pain. The combination of therapy and medical support made all the difference.”
Alyssa T.
Completed outpatient program, 2025
“I relapsed several times before finding Red Ribbon Recovery. They didn’t judge me, they adjusted my treatment plan and helped me find a strategy that worked. I’ve been clean for almost a year.”
Marcus P.
Completed outpatient program, 2025
“Before coming to Red Ribbon Recovery Indiana, I didn’t believe recovery was possible for me. I’d lost my job, my husband, and most of my confidence. The staff helped me rebuild my life from the inside out. I’m finally proud of the person I’m becoming.”
Jasmine L.
Completed outpatient program, 2025
Drug addiction by the numbers
Understanding the scope and impact of drug addiction in the United States
SAMSHA 2025
CDC 2024
NIH 2024
SAMHSA 2024
SAMHSA 2024
SAMHSA 2024
Warning signs & symptoms of drug addiction
Recognizing drug addiction early can be difficult because the symptoms vary depending on the substance and the person. However, certain patterns tend to appear across all types of addiction:
Physical signs
- Changes in sleep or appetite
- Sudden weight loss or gain
- Unexplained fatigue or energy bursts
- Bloodshot eyes or dilated pupils
- Neglected hygiene or appearance
- Needle marks, nosebleeds, or skin sores
Behavioral signs
- Secrecy or lying about whereabouts
- Financial problems or unexplained spending
- Decline in work or school performance
- Loss of interest in activities once enjoyed
- Legal issues or risky behavior
- Continuing to use despite negative consequences
Emotional signs
- Mood swings or irritability
- Anxiety or depression
- Guilt, shame, or hopelessness
- Withdrawal from loved ones
- Lack of motivation or apathy
Social signs
- Conflict with family or friends
- Association with new peer groups who use drugs
- Isolation or avoidance of social gatherings
- Disregard for responsibilities or relationships
Evidence-based treatment options
Drug and alcohol detox
Drug and alcohol detox, also known as medical detox, is the first step in recovery. It provides medical supervision to manage withdrawal symptoms safely. This short-term process at a drug rehab center helps individuals stabilize physically and prepare for ongoing substance use disorder treatment.
Inpatient treatment
An inpatient program, also known as residential addiction treatment, is a highly structured, 24/7 program that offers intensive therapy, medical support, and continuous supervision. This level of care is ideal for individuals who need a stable and supportive environment to begin their addiction recovery.
Day treatment program
Day treatment, also known as a partial hospitalization program, is the highest level of outpatient care, with programming scheduled four to five days a week. Some people start rehab in our day treatment program while others transition after completing inpatient treatment.
Intensive outpatient program
Intensive outpatient treatment meets three to four days a week, offering a combination of group therapy and individual sessions. Specialized programs are available to support diverse needs, including those for LGBTQ+ individuals, men, women and more.
Standard outpatient treatment
Standard outpatient treatment is a flexible option for individuals with mild substance use disorders or those transitioning from higher levels of care. Treatment typically includes scheduled therapy sessions that address addiction triggers, coping strategies, and ongoing challenges in maintaining sobriety.
Dual diagnosis treatment
Dual diagnosis treatment addresses both substance use and mental health disorders, recognizing that treating only one can worsen the other. This program begins with an assessment for an accurate diagnosis, followed by an integrated approach combining therapy, medication management, and supportive care.
Telehealth/virtual treatment
Telehealth provides access to therapy, counseling, and medication management through secure video or phone sessions. This approach makes care more accessible for people who cannot attend in person, offering flexibility while still maintaining professional support for mental health and substance use disorders.
The recovery process
Recovery from drug addiction is a gradual process that focuses on healing the body, mind, and spirit. It begins with stabilization and continues through therapy, lifestyle change, and community support.
Relapse is common, but it should be viewed as a signal to reassess and strengthen treatment—not as a failure. Long-term success depends on consistency, support, and personal commitment to change.
Stages of recovery
- Pre-contemplation. The person may not yet acknowledge a problem or may minimize its effects.
- Contemplation. Awareness of the consequences of drug use and consideration of treatment options.
- Preparation. Commitment to recovery and creation of a treatment plan.
- Action. Active participation in therapy, medication, and lifestyle changes.
- Maintenance. Continued practice of relapse prevention and healthy coping strategies.
Building a strong recovery foundation
- Develop coping strategies for cravings and stress
- Strengthen a reliable support network
- Address co-occurring mental health disorders
- Engage in meaningful activities or work
- Prioritize physical health and wellness
- Stay connected through aftercare programs
Family support resources
Addiction affects the entire family system. Loved ones often experience emotional distress, financial strain, and a loss of trust. Helping families heal is a vital part of the recovery process.
Family support options include:
- Al-Anon and Alateen. Peer-led groups where adults and teens can connect with others who have been affected by a loved one’s drug use and share practical ways of coping.
- Family therapy. Guided sessions with a trained therapist to work through communication issues, address conflict, and start rebuilding healthy relationships.
- Educational workshops. Programs that explain how drug addiction works, what recovery looks like, and how families can offer the right kind of support.
- Crisis helpline. Free, confidential phone lines that provide immediate help during emotionally difficult or unsafe situations.
- Community-based programs. Local resources that may offer peer mentoring, stress management classes, or skills training for caregivers.
When families have the right information, resources, and emotional support, they are in a much stronger position to encourage healthy boundaries, remain supportive without enabling, and take care of their own needs throughout the recovery journey.
Frequently asked questions
Where can I find drug addiction treatment in Indiana?
If you are seeking drug addiction treatment in Indiana, you will find a wide range of recovery centers located across the state. Many facilities are situated in major cities such as Indianapolis, Fort Wayne, Evansville, South Bend, Fishers, Bloomington, Lafayette, Gary, Muncie, Terre Haute, Elkhart, Kokomo, Richmond, Noblesville, and Carmel. Whether you live in the state’s largest metropolitan areas or smaller communities, drug addiction treatment options are available to help you or your loved one address alcohol use disorder and begin the path to recovery.
Several drug rehab centers in Indiana, including those in Indianapolis, Fort Wayne, Evansville, and South Bend, may provide transportation for individuals entering inpatient care and, in some cases, for those participating in outpatient services.
Our drug treatment facility is accessible for residents of Indiana and surrounding states. Conveniently located near Indiana University and major airports, our center is within driving distance of:
- Indianapolis, Indiana
- Fort Wayne, Indiana
- Evansville, Indiana
- South Bend, Indiana
- Bloomington, Indiana
- Carmel, Indiana
- Lafayette, Indiana
- Terre Haute, Indiana
- Kokomo, Indiana
- Muncie, Indiana
- Elkhart, Indiana
- Greenwood, Indiana
- Anderson, Indiana
- Noblesville, Indiana
- Fishers, Indiana
Our admissions coordinators are available to assist with travel arrangements and answer any questions about entering treatment. For ongoing recovery support, we also encourage participation in local and statewide community resources, including Narcotics Anonymous (NA) and other peer-led programs throughout Indiana.
How do I know if I or a loved one has drug addiction?
Drug addiction, clinically referred to as substance use disorder (SUD), can be identified by a combination of physical, behavioral, emotional, and social changes. Common indicators include:
- Needing more of the drug to achieve the same effect (increased tolerance)
- Experiencing withdrawal symptoms—such as anxiety, sweating, tremors, or nausea—when not using
- Using more frequently or in larger amounts than intended
- Making repeated unsuccessful attempts to cut down or quit
- Neglecting responsibilities at work, school, or home due to drug use
- Continuing to use despite health problems, relationship strain, or legal issues
- Spending significant time obtaining, using, or recovering from drugs
- Withdrawing from social events or activities that do not involve substance use
If you or someone close to you shows several of these warning signs, it may be time to seek a professional evaluation from a healthcare provider or addiction specialist. Early recognition and treatment can greatly improve recovery outcomes and reduce long-term health risks.
What are the short-term and long-term health risks of drug addiction?
Drug addiction can harm nearly every system in the body, and the severity of these effects depends on the type of substance used, the dose, and how long it has been used. Both short-term and long-term health risks can be serious and, in some cases, life-threatening.
Short-term risks
- Impaired judgment leading to accidents, injuries, or unsafe behaviors
- Overdose, which can result in respiratory failure, seizures, coma, or death
- Sudden changes in heart rate, blood pressure, or body temperature
- Nausea, vomiting, and dehydration
- Intense mood swings, agitation, or paranoia
- Sleep disturbances and exhaustion following periods of heavy use
Long-term risks
- Damage to major organs, including the heart, liver, kidneys, and lungs
- Lasting changes in brain structure and function, affecting memory, decision-making, and impulse control
- Increased risk of infectious diseases such as HIV or hepatitis (especially with injection drug use)
- Chronic respiratory or cardiovascular problems
- Hormonal and reproductive system disruptions
- Persistent mental health disorders, including anxiety, depression, and psychosis
- Malnutrition and weakened immune response, leaving the body more vulnerable to illness
Chronic drug misuse often leads to profound social and emotional consequences as well, including isolation, strained relationships, and financial or legal problems that compound the physical and psychological toll of addiction.
Can drug withdrawal be dangerous?
Yes. Drug withdrawal can be dangerous and, in some cases, life-threatening—particularly for individuals dependent on opioids, benzodiazepines, or other central nervous system depressants. When a person who has developed physical dependence suddenly stops or reduces their drug use, the brain and body must readjust to functioning without the substance. This can trigger a range of symptoms that vary depending on the drug involved, the duration of use, and overall health.
Common withdrawal symptoms
- Anxiety, irritability, or restlessness
- Muscle aches and joint pain
- Sweating or chills
- Nausea, vomiting, or diarrhea
- Headache or fatigue
- Insomnia or vivid dreams
- Intense drug cravings
Severe withdrawal symptomss
- Seizures or convulsions
- Hallucinations or delusions
- Irregular heart rate or high blood pressure
- Severe dehydration or electrolyte imbalance
- Suicidal thoughts or extreme mood swings
Because withdrawal from certain substances—especially opioids, benzodiazepines, and alcohol—can be medically complex, professional supervision is strongly recommended. A healthcare team can provide a safe environment, monitor vital signs, and use medications or supportive therapies to manage symptoms and prevent complications.
How is drug addiction diagnosed?
Drug addiction, clinically referred to as substance use disorder (SUD), is diagnosed by a qualified healthcare provider using established criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). The evaluation process helps determine the presence and severity of addiction and guides the most appropriate treatment approach.
- Clinical interview. A thorough discussion about drug use patterns, frequency, and related physical, psychological, or social effects. The clinician may also explore family history, mental health concerns, and past treatment attempts.
- Diagnostic criteria. Determining whether the individual meets two or more of the 11 DSM-5 criteria for substance use disorder within a 12-month period. These include symptoms such as cravings, tolerance, withdrawal, loss of control, and continued use despite harm.
- Physical examination. Assessing for complications related to substance use, such as cardiovascular problems, respiratory issues, or signs of infection related to injection drug use.
- Laboratory testing. Blood, urine, or hair testing may be used to confirm substance use, identify co-occurring medical issues, or monitor progress during treatment.
- Screening tools. Standardized assessments such as the DAST-10 (Drug Abuse Screening Test) or ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) may support the diagnostic process.
The severity of substance use disorder—classified as mild, moderate, or severe—is based on the number of criteria met and informs the individualized treatment plan that follows.
Is medical detox necessary for drug addiction?
Medical detox is often recommended for individuals with moderate to severe drug addiction, particularly when dependence has developed from prolonged or heavy use. Withdrawal from certain substances—such as opioids, benzodiazepines, or other central nervous system depressants—can cause serious medical complications if not properly managed.
During medical detox, healthcare professionals closely monitor vital signs, manage withdrawal symptoms, and may administer medications to ease discomfort, prevent seizures, or stabilize mood and heart rate. This process allows the body to safely eliminate drugs while minimizing the risk of complications such as dehydration, elevated blood pressure, or severe psychological distress.
While not everyone with drug addiction requires inpatient detox, attempting to quit abruptly without medical oversight can be unsafe. A supervised detox program provides the safest foundation for recovery and helps prepare individuals for the next stage of care, such as residential treatment, partial hospitalization, intensive outpatient or standard outpatient therapy.
How long does drug addiction treatment usually last?
The duration of drug addiction treatmentvaries based on the substance involved, the severity of dependence, and the individual’s progress throughout recovery. Some people respond well to short-term programs, while others benefit from several months or more of structured care to support lasting change.
Typical treatment timelines include:
- Medical detox. Usually 5 to 14 days, depending on the substance and severity of withdrawal.
- Residential or inpatient rehab. Commonly 30, 60, or 90 days, though some individuals remain in care for six months or longer for sustained stabilization.
- Partial hospitalization or intensive outpatient programs. Often last several weeks to a few months, with therapy sessions held multiple times per week.
- Standard outpatient treatment. May continue for many months or years as part of long-term maintenance and relapse prevention.
Recovery from drug addiction is an ongoing process that extends beyond formal treatment. Continued therapy, peer support, medication management, and structured aftercare are key to maintaining long-term recovery and preventing relapse.
Can a person recover from drug addiction?
Yes. Recovery from drug addiction is absolutely possible. While addiction is a chronic, relapsing condition, it can be effectively managed with the right combination of medical care, therapy, and long-term support. Recovery involves more than simply stopping drug use—it includes restoring physical health, emotional balance, and daily functioning.
What are the 5 stages of drug addiction?
Drug addiction typically develops gradually through a series of identifiable stages:
- Experimentation. Initial, voluntary use—often driven by curiosity, peer influence, or stress.
- Regular use. The individual begins using drugs more frequently, often to relax or cope with emotional difficulties.
- Risky use. Substance use starts to cause problems, such as changes in behavior, poor decision-making, or neglect of responsibilities.
- Dependence. The body and brain adapt to the substance, leading to tolerance and withdrawal symptoms when use is reduced or stopped.
- Addiction. Drug use becomes compulsive, with strong cravings and continued use despite clear harm to health, relationships, or work.
Recognizing where someone falls within these stages can help determine the most effective point for intervention and treatment.
Is addiction a mental illness?
Yes. Addiction is recognized as a mental illness because it affects the brain’s structure, chemistry, and function, leading to compulsive behavior despite negative consequences. The changes occur in areas of the brain that control judgment, impulse regulation, motivation, and emotion, making it difficult for a person to stop using even when they want to.
Like other mental health disorders, addiction often coexists with conditions such as depression, anxiety, or post-traumatic stress disorder (PTSD). Effective treatment addresses both the psychological and physical aspects of addiction through integrated care, combining therapy, medication, and behavioral support.
Sources
- Substance Abuse and Mental Health Services Administration. (2025). Results from the 2024 National Survey on Drug Use and Health: Detailed Tables.
- Centers for Disease Control and Prevention. (2025). Provisional Drug Overdose Death Counts, 2024.
- National Institute on Drug Abuse. (August 21, 2024). Drug Overdose Deaths: Facts and Figures.
- American Psychiatric Association. (2022). Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing.
- Volkow, N. D., Koob, G. F., & McLellan, A. T. (January 28, 2016). Neurobiologic Advances from the Brain Disease Model of Addiction. New England Journal of Medicine, 374(4), 363–371.
- National Institute of Mental Health. (March 2025). Substance Use and Co-Occurring Mental Disorders.
- National Institute on Drug Abuse. (July 6, 2020). Drugs, Brains, and Behavior: The Science of Addiction
Substance Abuse and Mental Health Services Administration. (2021). Medications for Opioid Use Disorder (Treatment Improvement Protocol 63).
About the content

Written by: Carli Simmonds. Carli Simmonds holds a Master of Arts in Community Health Psychology from Northeastern University. From a young age, she witnessed the challenges her community faced with substance abuse, addiction, and mental health challenges, inspiring her dedication to the field.

Medical reviewed by: Jodi Tarantino, LICSW. Jodi Tarantino is an experienced, licensed Independent Clinical Social Worker (LICSW) and Program Director with over 20 years of experience in Behavioral Healthcare. Also reviewed by the RRR Editorial team.
Red Ribbon Recovery is committed to delivering transparent, up-to-date, and medically accurate information. All content is carefully written and reviewed by experienced professionals to ensure clarity and reliability. During the editorial and medical review process, our team fact-checks information using reputable sources. Our goal is to create content that is informative, easy to understand and helpful to our visitors.

